Immuno-histochemical assessment of hENT1 biomarker as a prognostic biomarker for patients undergoing gemcitabine-based chemotherapy for resected biliary tract cancers: A systematic review and meta-analysis
نویسندگان
چکیده
منابع مشابه
Gemcitabine sensitivity factors, hENT1 and RRM1 as potential prognostic biomarker for advanced biliary tract cancer.
BACKGROUND AND AIMS Biliary tract caner (BTC) is one of rare malignant disease with poor prognosis. Gemcitabine has been widely used as chemotherapeutic agent for advanced BTC treatment. Several molecules involved in gemcitabine metabolism, including human equilibrative nucleoside transporter (hENT1) and ribonucleotide reductase subunit M1 (RRM1), have been investigated as predictive biomarkers...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2016
ISSN: 0923-7534
DOI: 10.1093/annonc/mdw363.75